Dermoscopic changes in melanocytic nevi covered with both an opaque tape and sunscreen cream during narrowband ultraviolet B therapy
Keywords:
dermoscopy, sunscreen, melanocytic nevus, photherapy, narrowband ultraviolet BAbstract
Background: Ultraviolet (UV) light may cause dermoscopic changes on melanocytic nevi (MN).
Objectives: To investigate the effects of sunscreen (SSc) application on dermoscopic changes in MN during narrow band UVB (NBUVB) therapy.
Methods: Half of the randomly selected MN in each patient were covered with opaque tape and SSc [SSc(+)], and the rest were covered with only opaque tape [SSc(-)] during NBUVB treatment sessions.
Results: A larger proportion SSc(-) MN displayed dermoscopic changes at end of NBUVB therapy compared to the start of therapy (p=0,035). The number of the MN that decreased in size and showed loss of structure was significantly higher in SSc(-) MN (p=0.04 and p=0.026, respectively).
Conclusions: Sunscreen in combination with opaque tape may contribute to some dermoscopic changes in melanocytic nevi, including decrease in size and loss of structure.
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