Satisfactory treatment of an operable connective tissue nevus with intralesional steroid injection

Satisfactory treatment of an operable connective tissue nevus with intralesional steroid injection

Authors

  • Nasrin Saki Molecular Dermatology Research Center, Shiraz University of Medical Sciences & Dermatology Department, Shiraz University of Medical Sciences, Shiraz, Iran
  • Azadeh Dorostkar Molecular Dermatology Research Center, Shiraz University of Medical Sciences & Dermatology Department, Shiraz University of Medical Sciences, Shiraz, Iran
  • Alireza Heiran Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  • Fatemeh Sari Aslani Molecular Dermatology Research Center & Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran

Keywords:

collagenoma, isolated collagenoma, connective tissue nevus, steroid

Abstract

Collagenoma is a type of connective tissue nevi, a rare hamartomatous malformation characterized by the predominant proliferation of normal collagen fibers and normal, decreased, or increased elastic fibers. Collagenomas present as multiple or solitary, hereditary or sporadic, asymptomatic, skin-colored papules, nodules, and plaques with variable sizes, and are usually located on the trunk, arm, and back. Here, we report on a 14-year-old boy who presented with an isolated giant collagenoma of the frontal area that dramatically responded to intralesional triamcinolone acetonide.

References

Botella-Estrada R, Alegre V, Sanmartin O, Ros C, Aliaga A. Isolated plantar cerebrifirm collagenoma. Arch dermatol, 1991; 127(10):1589-90. PMID: 1929476.

Jones MS, Helm KF. A solitary warty plaque. Isolated cerebriform collagenoma. Arch Dermatol. 1997; 133(7):911-2. PMID: 9236533.

Kumar S, Singh SK, Banasal A, Banasal M. Isolated collagenoma on the scalp: a rare presentation. Int J Tricology. 2013; 5(2):88. PMID: 24403773. DOI: 10.4103/0974-7753.122969.

Amato L, Mei S, Gallerani I, Moretti S, Cipollini EM, Palleschi GM, et al. Familial cutaneous collagenoma: report of an affected family. Int J Dermatol. 2005; 44(4):315-7. PMID: 15811085.

Boente Mdel C, Primc NB, Asial RA, Winik BC. Familial cotaneous collagenoma: a clinicopathologic study of two new cases. Pediatr Dermatol. 2004; 21(1):33-8. PMID: 14871323.

Ju Q, Song N, Sun J. Eruptive cutaneous collagenoma in a Chinese patient. J Dermatol. 2011; 38(4):399-401. PMID: 21352340.

Yahya H, Rafindadi AH. Eruptive collagenoma in Nigerian girl. Int J Dermatol. 2006; 45(11):1344-6. PMID: 17076722.

Madke B, Doshi B, Nayak C, Prasannan R. Isolated pedunculated collagenoma (collagen nevi) of the scalp. Indian J Dermatol. 2013; 58(5):411. PMID: 24082230.

Togawa Y, Nohira G, Shinkai H, Utani A. Collagenoma in down syndrome. Br J Dermatol. 2003; 148(3):596-7. PMID: 12653762.

Kakinoma Y, Endo H, Tsukahara T, Futoeda T, Saito Y, Shinkai H. Collagenoma with pseudohypoparathyroidism. Br J Dermatol. 2000; 143(5):1122-4. PMID: 11069551.

Sacks HN, Crawley IS, Ward JA, Fine RM. Familial cardiomyopathy, hypogonadism, and collagenoma. Ann Intern Med. 1980; 93(6):813-7. PMID: 7447187.

Nico MM, Valente NY, Machado KA. Isolated plantar collagenoma. Acta Derm Venereol. 2003; 83(2):144. PMID: 12735651.

- Uitto J, Bauer EA, Santa Cruz DJ, Holtmann B, Eisen AZ. Decreased collagenase production by regional fibroblasts cultured from skin of a patient with connective tissue nevi of the collagen type. J Invest Dermatol 1982; 78:136–40. PMID: 6276472.

Romiti R, Romiti N. Papulolinear collagenoma. J Am Acad Dermatol. 2004; 50:797-8. PMID: 15097970.

AI-Breiki SH, Bukhari IA. Childhood solitary collagenoma. Saudi Med J. 2006; 27(3):395-6. PMID: 16532106.

Dawn ME, Deng AC, Petrali J, Wessely C, Jaffe D, Gaspari AA. Familial cutaneous collagenoma. Skinmed 2008; 7:43–5. PMID: 18174804.

Sardana K, Bansal S, Garg VK, Khurana N. Linear nodular collagenoma – successful treatment with intralesional triamcinolone acetonide. Pediatr Dermatol 2009; 26:626–8. PMID: 19840332.

- Yadav S, Khullar G, Saikia UN, Dogra S. Isolated corymbose collagenoma responding to intralesional triamcinolone acetonide and hyaluronidase injections. Dermatol ther. 2013; 26(5):419-23. PMID: 24099074.

Robles DT, Berg D. Abnormal wound healing: keloids. Clin dermatol. 2007; 25(1):26-32. PMID: 17276198. DOI: 10.1016/j.clindermatol.2006.09.009.

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Published

2018-01-31

Issue

Section

Observation

How to Cite

1.
Saki N, Dorostkar A, Heiran A, Sari Aslani F. Satisfactory treatment of an operable connective tissue nevus with intralesional steroid injection. Dermatol Pract Concept. 2018;8(1). Accessed October 26, 2025. https://www.dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp0801a03

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