Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma

Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma

Authors

  • Philipp Tschandl Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
  • Leonhard Müllauer Department of Pathology, Medical University of Vienna
  • Harald Kittler Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria

Keywords:

CCML, systemic mastocytosis, leukemia, xanthogranuloma

Abstract

A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis. A consequently performed bone marrow biopsy verified a systemic mastocytosis and a chronic myelomonocytic leukemia (CMML) type I. Here, we describe for the first time in the literature a patient with three diseases occurring synchronously: CMML, xanthogranulomas and systemic mastocytosis. Two of them at a time are known to be associated and may be indicative of a common progenitor cell.

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Published

2012-07-31

Issue

2012 Vol 2, No 3 | July

Section

Observation

License

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

1.
Tschandl P, Müllauer L, Kittler H. Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma. Dermatol Pract Concept. Published online July 31, 2012:13-16. Accessed October 26, 2025. https://www.dpcj.org/index.php/dpc/article/view/dermatol-pract-concept-articleid-dp0203a03

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