Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

Marie Hélène Jegou Penouil; Jean-Yves Gourhant; Catherine Segretin; David Weedon; Cliff Rosendahl

doi:10.5826/dpc.0402a09

Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

Authors

Marie Hélène Jegou Penouil Cabinet de Dermatologie, Blanquefort, France
Jean-Yves Gourhant Centre de Dermatologie, Nemours, France
Catherine Segretin Cabinet d’anatomopathologie, Talence, France
David Weedon Sullivan Nicolaides Pathology, Brisbane, Australia
Cliff Rosendahl School of Medicine, The University of Queensland, Australia

Keywords:

dermatoscopy, dermoscopy, dermatopathology, yellow melanoma, hypomelanotic melanoma, lipofuscin, Sudan Black

Abstract

A case of a predominantly yellow primary superficial spreading melanoma arising on the back of a 44-year-old woman is presented. Possible causes of the clinical and dermatoscopic yellow color are discussed. Staining with the histochemical stain, Sudan Black, revealed a differential uptake compared to a closely matched control melanoma. We speculate that the clinical and dermatoscopic yellow color could be due to the presence of increased amounts of the pigment lipofuscin, which is known to produce subtle orange color in some choroidal melanomas.

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Published

2014-04-30

Issue

2014 Vol 4, No 2 | April

Section

Observation

License

Dermatology Practical & Conceptual applies a Creative Commons Attribution License (CCAL) to all works we publish (http://creativecommons.org/licenses/by-nc/4.0/). Authors retain the copyright for their published work.

How to Cite

Jegou Penouil MH, Gourhant JY, Segretin C, Weedon D, Rosendahl C. Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report. Dermatol Pract Concept. Published online April 30, 2014:45-49. doi:10.5826/dpc.0402a09