Spitz and Reed nevi: acquired or congenital?

Spitz and Reed nevi: acquired or congenital?

Authors

  • Michael Bär Dermatology office, Bautzen, Germany

Keywords:

Spitz nevus, Reed nevus, congenital nevus, acquired nevus, melanocytic nevus, nevogenesis, classification

References

Ackerman AB, Cerroni L, Kerl H. Pitfalls in Histopathologic Diagnosis of Malignant Melanoma. Philadelphia: Lea & Febiger, 1994.

Happle R. Mosaicism in human skin. Understanding the patterns and mechanisms. Arch Dermatol. 1993; 129(11):1460-70.

Happle R. What is a nevus? A proposed definition of a common medical term. Dermatology. 1995;191(1):1-5.

Kittler H, Rosendahl C, Cameron A, Tschandl P. Dermatoscopy. An Algorithmic Method Based on Pattern Analysis. Vienna: Facultas.wuv, 2011.

Cramer SF. Speckled lentiginous nevus (nevus spilus): the “roots” of the “melanocytic garden.” Arch Dermatol. 2001;137(12):1654-5.

Schaffer JV, Orlow SJ, Lazova R. Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi. Arch Dermatol. 2001;137(2):172-8. .

Bolognia JL, Jorizzo JL, Rapini RP. Dermatology. 2nd ed. New York: Mosby Elsevier, 2008.

Krengel S. Nevogenesis-new thoughts regarding a classical problem. Am J Dermatopathol. 2005;27(5):456-65.

Zalaudek I, Hofmann-Wellenhof R, Kittler H, et al. A dual concept of nevogenesis: Theoretical considerations based on dermoscopic features of melanocytic nevi. J Dtsch Dermatol Ges. 2007;5(11): 985-92.

Rhodes AR. Congenital nevomelanocytic nevi. Histologic patterns in the first year of life and evolution during childhood. Arch Dermatol. 1986;122(11):1257-62.

Mark GJ, Mihm MC, Liteplo MG, Reed RJ, Clark WH. Congenital melanocytic nevi of the small and garment type. Clinical, histologic and ultrastructural studies. Hum Pathol. 1973;4(3):395-418.

BÖer A. More than a third of all lesions diagnosed clinically as Clark’s or dysplastic nevi are unequivocally congenital nevi on histopathological diagnosis. Dermatopathology: Practical & Conceptual. 2007;13(2):5. http://derm101.com/content/32568; accessed May 1, 2012.

Harada K, Ackerman AB. Less than 10% of primary cutaneous melanomas, worldwide, are associated with a melanocytic nevus and that nevus usually is congenital, not “dysplastic.” Dermatopathology: Practical & Conceptual. 2005;11(2):3. http://derm101.com/content/32373; accessed May 1, 2012.

Kittler H, Seltenheim M, Dawid M, Pehamberger H, Wolff K, Binder M. Frequency and characteristics of enlarging common melanocytic nevi. Arch Dermatol. 2000;136(3):316-20.

Argenziano G, Zalaudek I, Ferrara G, Hofmann-Wellenhof R, Soyer HP. Proposal of a new classification system for melanocytic naevi. Br J Dermatol. 2007;157(2):217-27.

Grichnik JM. Melanoma, nevogenesis, and stem cell biology. J Invest Dermatol. 2008;128(10):2365-80.

Dadzie OE, Goerig R, Bhawan J. Incidental microscopic foci of nevic aggregates in skin. Am J Dermatopathol. 2008;30(1):45-50.

Ackerman AB, Milde P. Naming acquired melanocytic nevi. Common and dysplastic, normal and atypical, or Unna, Miescher, Spitz, and Clark? Am J Dermatopathol. 1992;14(5):447-53.

Ackerman AB, Magana-Garcia M. Naming acquired melanocytic nevi. Unna’s, Miescher’s, Spitz’s Clark’s. Am J Dermatopathol. 1990;12(2):193-209.

Zalaudek I, Hofmann-Wellenhof R, Soyer HP, Ferrara G, Argenziano G. Naevogenesis: new thoughts based on dermoscopy. Br J Dermatol. 2006;154(4): 793-4. .

Ackerman AB, Elish D, Shami S. “Spitz’s nevus”: Reassessment Critical, Revision Radical. New York: Ardor Scribendi Ltd., 2007.

Massi G, LeBoit P. Histological Diagnosis of Nevi and Melanoma. Darmstadt: Steinkopff Verlag, 2004.

Harris MN, Hurwitz RM, Buckel LJ, Gray HR. Congenital Spitz nevus. Dermatol Surg. 2000;26(10):931-5.

Glasgow MA, Lain EL, Kincannon JM. Agminated Spitz nevi: report of a child with a unique dermatomal distribution. Pediatr Dermatol. 2005;22(6):546-9.

Kilinc Karaarslan I, Ozdemir F, Akalin T, Ozturk G, Turk BGH, Kandiloglu G. Eruptive disseminated Spitz naevi: dermatoscopic features. Clin Exp Dermatol. 2009;34(8):e807-10.

Hamm H, Happle R, Brocker EB. Multiple agminate Spitz naevi: review of the literature and report of a case with distinctive immunohistological features. Br J Dermatol. 1987;117(4):511-22.

Hulshof MM, van Haeringen A, Gruis NA, Snels DC, Bergman W. Multiple agminate Spitz naevi. Melanoma Res. 1998;8(2):56-60.

Levy RM, Ming ME, Shapiro M, et al. Eruptive disseminated Spitz nevi. J Am Acad Dermatol. 2007;57(3):519-23.

Palazzo JP, Duray PH. Congenital agminated Spitz nevi: immunoreactivity with a melanoma-associated monoclonal antibody. J Cutan Pathol. 1988;15(3):166-70.

Renfro L, Grant-Kels JM, Brown SA. Multiple agminate Spitz nevi. Pediatr Dermatol. 1989;6(2):114-7.

Zaenglein AL, Heintz P, Kamino H, Zisblatt M, Orlow SJ. Congenital Spitz nevus clinically mimicking melanoma. J Am Acad Dermatol. 2002;47(3):441-44.

Song JY, Kwon JA, Park CJ. A case of Spitz nevus with multiple satellite lesions. J Am Acad Dermatol. 2005;52(2Suppl 1):48-50.

Aida K, Monia K, Ahlem S, et al. Agminated Spitz nevi arising on a nevus spilus after chemotherapy. Pediatr Dermatol. 2010;27(4):411-3.

Aloi F, Tomasini C, Pippione M. Agminated Spitz nevi occurring within a congenital speckled lentiginous nevus. Am J Dermatopathol. 1995;17(6):594-8.

Betti R, Inselvini E, Palvarini, M, Crosti C. Agminated intradermal Spitz nevi arising on an unusual speckled lentiginous nevus with localized lentiginosis: a continuum? Am J Dermatopathol. 1997;19(5):524-7.

BÖer A, Wolter M, Kneisel L, Kaufmann R. Multiple agminated Spitz nevi arising on a cafe au lait macule: review of the literature with contribution of another case. Pediatr Dermatol. 2001;18(6):494-7.

Haenssle HA, Kaune KM, Thoms KM. Large speckled lentiginous naevus superimposed with Spitz naevi: sequential digital dermoscopy may lead to unnecessary excisions triggered by dynamic changes. Clin Exp Dermatol. 2009;34(2):212-5.

Herd RM, Allan SM, Biddlestone L, Buxton PK, McLaran KM. Agminate Spitz naevi arising on hyperpigmented patches. Clin Exp Dermatol. 1994;19(6):483-6.

BÄr M, Tschandl P, Kittler H. Differentiation of pigmented Spitz nevi and Reed nevi by integration of dermatopathologic and dermatoscopic findings. Dermatol Pract Conc. 2012;2(1):3. http://www.dx.doi.org/10.5826/dpc.0201a03.

Borsa S, Toonstra J, van der Putte SC, van Vloten WA. [Balloon-cell variant of the Spitz nevus]. Hautarzt. 1991;42(11):707-8.

Mooi, W. J. Histopathology of Spitz naevi and “spitzoid” melanomas. Curr Top Pathol. 2001;94:65-77.

Argenziano G, Scalvenzi M, Staibano S. Dermatoscopic pitfalls in differentiating pigmented Spitz nevi from cutaneous melanomas. Br J Dermatol. 1999;141(5):788-93.

Barnhill RL, Barnhill MA, Berwick M, Mihm MC Jr. The histologic spectrum of pigmented spindle cell nevus: a review of 120 cases with emphasis on atypical variants. Hum Pathol. 1991;22(1):52-58.

Reed RJ, Ichinose H, Clark WH Jr, Mihm MC Jr. Common and uncommon melanocytic nevi and borderline melanomas. Semin Oncol. 1975;2(2):119-47.

Kutzner H, SchÄrer L, Requena L. [Epithelioid and hyperpigmented melanocytic tumors. An overview]. Pathologe. 2007;28(6):411-21.

Sau P, Graham JH, Helwig EB. Pigmented spindle cell nevus: a clinicopathologic analysis of ninety-five cases. J Am Acad Dermatol. 1993;28(4):565-71.

Sowa J, Kobayashi H, Ishii M, Kimura T. Histopathologic findings in Unna’s nevus suggest it is a tardive congenital nevus. Am J Dermatopathol. 2008;30(6):561-6.

Marghoob AA, Blum R, Nossa R, Busam KJ, Sachs D, Halpern A. Agminated atypical (dysplastic) nevi. Arch Dermatol. 2001;137(7):917-20.

Requena C, Requena L, Kutzner H, Sanchez-Yus E. Spitz nevus: a clinicopathological study of 349 cases. Am J Dermatopathol. 2009;31(2): 107-16.

Poynter JN, Elder JT, Fullen DR, et al. BRAF and NRAS mutations in melanoma and melanocytic nevi. Melanoma Res. 2006;16(4):267-73.

Gill M, Celebi JT. B-RAF and melanocytic neoplasia. J Am Acad Dermatol. 2005;53(1):108-14.

Gill M, Renwick N, Silvers DN, Celebi JT. Lack of BRAF mutations in Spitz nevi. J Invest Dermatol. 2004; 122(5):1325-6.

Bauer J, Curtin JA, Pinkel D, Bastian BC. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. J Invest Dermatol. 2007;127(1):179-82.

Ross AL, Sanchez MI, Grichnik JM. Molecular nevogenesis. Dermatol Res Pract. 2011;2011:463184. Epub 2011 Apr 6.

Nikai H, Miyauchi M, Ogawa I, Takata T, Hayashi Y, Okazaki H. Spitz nevus of the palate. Report of a case. Oral Surg Oral Med Oral Pathol. 1990;69(5):603-8.

Downloads

Published

2012-07-31

Issue

Section

Commentary

How to Cite

1.
Bär M. Spitz and Reed nevi: acquired or congenital?. Dermatol Pract Concept. Published online July 31, 2012:21-27. doi:10.5826/dpc.0203a05

Share